4-Methylcyclohexanemethanol (MCHM, systematic name 4- methylcyclohexylmethanol) is an Eastman Chemical Company’s MSDS for ” crude” (unpurified) MCHM, as supplied by NPR, reports an oral LD of mg/ kg and a dermal LD Product Name. 4-Methylcyclohexanol, mixture of cis and trans. Cat No. Details of the supplier of the safety data sheet. Emergency Telephone. 4-Methylcyclohexanemethanol (cis- and trans- mixture) 1-(Hydroxymethyl)-4 -methylcyclohexane. 4. FIRST-AID MEASURES SAFETY DATA SHEET.

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Cyclohexanemethanol or cyclohexylmethanolCHM, CASanother closely related compound, which differs only in lacking a methyl substituent, has been found as a naturally occurring fusel alcohol in mango wine at concentrations of 1.

Views Read Edit View history. Epimeric alcohols of the cyclohexane series. The ChemSpider entry for MCHM indicates that it has been evaluated for ligand activity via SimBioSys ‘s LASSO analysis, which predicted low to no activity on 40 biologically significant receptorsindicating a low likelihood for significant biological activity on them.

A WHO study concluded that p -menthanol was of “no safety concern” for human consumption at high levels of 2.

4-Methylcyclohexanemethanol – Wikipedia

From Wikipedia, the free encyclopedia. MCHM has the advantage of being less toxic than previous frothing agents containing 2-ethylhexanol. Retrieved 19 January Ullmann’s Encyclopedia of Industrial Chemistry.


One web site, Fantastic Flavours provides a list of recognized flavor additives for Japan, which includes 2,4-dimethylcyclohexanemethanol by virtue of being in the group of aliphatic higher alcohols. Classified as a saturated higher alicyclic primary alcohol. By using this site, you agree to the Terms of Use and Privacy Policy.

Another CHM derivative, 2,4-dimethylcyclohexanemethanol CASalso dihydrofloralol or floral methanolwhich has two methyl substituents instead of one, is frequently marketed as a fragrance or flavor additive. Reliable information on health and safety of this compound is limited.

Target pollutants and treatment objectives” PDF. This page was last edited on 10 Decemberat It has been patented for use in air fresheners.

Commercial samples of MCHM consists of a mixture of these msthylcyclohexane as well as other components that vary with the supplier. Safety evaluation of certain food additives and contaminants PDF. Both cis and trans isomers exist, depending on the relative positions of the methyl CH 3 and hydroxymethyl CH 2 OH groups on the cyclohexane ring.


Other names 1- hydroxymethyl methylcyclohexane 4-methylcyclohexylcarbinol MCHM hexahydro- p -tolyl-carbinol archaic. Languages Deutsch Edit links. International Programme on Chemical Safety.

However, a longer-term six-week repetition of that test as a sensitization study failed to produce any reactions. US Patent Application No. Food and Chemical Toxicology. Other cyclohexane -based alcohols can also be used.


The solubility of 1-octanol in water is 2.

Indian Journal of Microbiology. It is also produced as a byproduct ca.

4-Methylcyclohexanemethanol | C8H16O – PubChem

Retrieved methylcycloehxane June Journal of the Chemical Society, Transactions. The toxicity and environmental methylcclohexane of these naphthenic acids have been well studied recently due to their occurrence as a major contaminant in water used for extraction of oil from tar sands.

Retrieved 18 January Refractive index n D. CHM with a methylethyl or isopropyl substituent group at the same position as the methyl group in 4-methylcyclohexanemethanol cis 1-methylethyl cyclohexane methanol, CAS is regarded as a flavoring and fragrance agent, sometimes listed under the synonym p -menthanol, and was the subject of a review article on its toxicological and dermatological properties in It is a colourless emthylcyclohexane with a faint mint-like alcohol odor.

It was first prepared in by Bouveault—Blanc reduction of a methylcyclohexanecarboxylate ester.

Journal of Environmental Engineering and Science. Canadian Journal of Research.